Ulawulo loXinzelelo lwe-NaOH kwi-Organic Intermediate Synthesis

Kwi-complex organic intermediate synthesis, ulawulo oluchanekileyo lwe-sodium hydroxide (NaOH) concentration luphawu oluphambili lomgangatho wemveliso, ukusebenza kakuhle kwenkqubo, kunye nenzuzo. Ukusetyenziswa kwe-NaOH ekuhlanganiseni i-organic intermediates ezifana ne-phenoxide salts kunye ne-alkoxide salts kudlala indima ebalulekileyo ekuvelisweni kweedayi, amayeza, kunye nezinto ze-polymeric, njengoko ezi intermediates zisebenza njengezinto ezibalulekileyo zokwakha ukuvelisa ii-organic compounds ezinexabiso eliphezulu.

Ukuze kwenziwe i-phenoxide kunye ne-alkoxide salts, indlela esebenza ngayo i-NaOH isekelwe kwi-alkalinity yayo enamandla. Ngokusebenzisa itekhnoloji yokuva i-inline ultrasonic, inkqubo yokwenziwa kwe-NaOH inokubekwa esweni ngexesha langempela kumanqanaba ahlukeneyo.

Jonga ezinye ii-Applications

Ubunzima kuLawulo loXinzelelo lwe-NaOH kwi-Organic Intermediate Synthesis

Ukulawula uxinano lwe-NaOH kwi-organic intermediate synthesis kuveza imingeni ebalulekileyo enxulumene neempawu zayo zeekhemikhali kunye ne-process dynamics. Ukunyibilika kwayo okuncinci kwi-organic solvents kubangela imvula, ngelixa ukuxubana okungekho semgangathweni kwi-reactors ezinkulu kudala i-concentration gradients—nto leyo ethintela ukwakheka kwe-phenoxide/alkoxide efanayo.

Ukunyibilika/ukusabela kwayo okungaphandle kobushushu (ΔH = -44.51 kJ/mol) kubangela ukunyuka kobushushu, okuphazamisa ukulingana (umz., ukutshintsha i-alkoxide synthesis ukuya kwi-hydrolysis) kunye nokufumisa izinyibilikisi ezibila kancinci ezifana ne-ethanol. Ukuguquguquka kwe-pH okuxhomekeke kuxinzelelo kukwabeka emngciphekweni iimpendulo ezingalindelekanga: >1.0 M NaOH ikhuthaza iimpendulo zeCannizzaro kwi-Claisen-Schmidt condensations, ngelixa <2.5 M ithintela i-Kolbe-Schmitt carboxylation.

Ukongeza, i-NaOH ifunxa i-CO₂/umswakama ukuze yenze i-Na₂CO₃ engcolisayo, kwaye ukujonga ngexesha langempela kuyathintelwa kukuhamba kancinci okanye ukungcoliswa kwemitha ye-pH kwizinto eziphilayo. I-NaOH exineneyo (≥10 M) idla ngokutya ii-reactors, nto leyo ebangela iingxaki zolawulo.

Ngaba unemibuzo malunga nokwenza ngcono iinkqubo zemveliso?

Unxibelelwano neeNjineli

Iindawo zoFakelo lweeMetha zoXinaniso kwi-Intanethi kuLawulo loXinaniso lwe-NaOH

Iimitha zoxinano ezikwi-intanethi zifakelwe ikakhulu kwiikhonkco eziphambili zenkqubo ezine, zigxile ekujongeni ukugxila kwezisombululo ze-NaOH ngexesha langempela ukuqinisekisa uzinzo lwenkqubo:

Ukulungiswa kweNaOH kwiZinto eziluhlaza

Xa kulungiswa i-NaOH eqinileyo kwizisombululo ezidityanisiweyo ezifunekayo kwinkqubo,uxinzelelo lwe-sodium hydroxideimithaifakelwe kwii-outlkunye mixingIguqula uxinano olulinganisiweyo lube luxinano ngexesha langempela, ithintela iimpazamo ezivela ekuqokeleleni ngesandla kwaye iqinisekisa ukuchaneka koxinano lwe-feedstock.

Unyango lwangaphambi konyango lweReaction Feed

Ngaphambi kokuba isisombululo se-NaOH sifakwe kwi-reactor,isivamvo soxinzelelo lwe-sodium hydroxideifakelwe kumbhobho we-NaOH feed. Iqinisekisa ukuthotyelwa koxinzelelo ukuze kuthintelwe ukwakheka okungonelanga okuphakathi okujoliswe kuko okanye iimpembelelo ezibangelwa kuxinzelelo olungekho kwi-spec.

Ukubeka esweni iNgxaki yokuphendula

Kwiimpendulo apho uxinaniso lwe-NaOH lutshintsha ngokuguquguqukayo, imitha yoxinaniso ifakwe kumbhobho wokujikeleza kwangaphakathi kwe-reactor okanye kumbhobho wesampulu ye-outlet. Ilandelela ukuguquguquka koxinaniso ngexesha langempela ukuze iqondise ukwakheka kwe-NaOH ngexesha elifanelekileyo, iphephe i-hydrolysis okanye impendulo engaphelelanga.

Ukubuyisela/Ukuhlamba Emva Kokusabela

Ukuba i-NaOH engaphendulwanga iphinda isetyenziswe okanye isetyenziselwa ukuhlamba imveliso, imitha yoxinano ifakwa kwindawo yokugcina ulwelo lokubuyisela. Ijonga uxinano lwe-NaOH ephinda isetyenziswe, igqibe ukuba iyayinyibilikisa okanye yongeze, kwaye iqinisekise ukuba uxinano lolwelo lokuhlamba luyahlangabezana neemfuno zobumsulwa (umz., ukuthintela intsalela ye-NaOH eninzi kwiindawo eziphakathi).

Funda Ngakumbi ngeeMetha zoBuxinano

Imitha yoxinano lwe-slurry engeyoyenyukliya

Imitha yoXinzelelo lweeKhemikhali

Imitha yoXinzelelo lwe-H₂O₂ ekwi-Inline

Imitha yoXinzelelo lwe-Ethanol kwi-Intanethi

Iingenelo Eziziswa Yimitha Yokuxinanisa iSodium Hydroxide

Imitha yoxinaniso ye-sodium hydroxide (NaOH) inika ixabiso elibalulekileyo kwi-organic intermediate synthesis ngokujongana nemingeni ephambili yokulawula uxinaniso, kunye neenzuzo eziphambili ngolu hlobo lulandelayo:

●MnatIvumela ukujonga ngexesha langempela, ngokuchanekileyo, ithatha indawo yeendlela ezicothayo, ezingaxhunyiwe kwi-intanethi ezifana ne-titration. Ngokuguqula uxinano lube luxinzelelo ngoko nangoko, iqinisekisa ukuba i-NaOH ihlala ngaphakathi koluhlu olujoliswe kulo, iphephe ukuthotywa ngaphantsi okanye ukuthotywa ngaphezulu.

●MnaI-t inyusa uzinzo lwenkqubo kunye nokuhambelana kwemveliso. Ngokuthintela ukusetyenziswa kwe-NaOH ngokugqithisileyo kunye nokuvumela ukurisayikilishwa ngokuchanekileyo kwe-NaOH engaphendulwanga, inciphisa iindleko zezinto kwaye inciphise umthwalo wonyango lwenkunkuma.

●IIphucula ukhuseleko kunye nokuthobela imithetho. Izilumkiso zexesha langempela zoxinzelelo olungaqhelekanga zinciphisa umngcipheko wokugqwala kwe-reactor okanye ukubaleka kwe-exothermic. Ukongeza, umsebenzi wayo wokurekhoda idatha uhlangabezana neemfuno zolawulo zokulandelela kumashishini afana namayeza, okwenza kube lula iinkqubo zophicotho-zincwadi.