Txhua qhov txuas ntawm kev tsim khoom tseem ceeb rau kev sib tw ntawm lub tuam txhab thaum sib tw nrog kev sib tw hnyav hauv kev lag luam biopharmaceutical. Piv txwv li, kev tsim cov tshuaj temsirolimus concentrated rau kev txhaj tshuaj. Txawm tias qhov kev hloov pauv me me ntawm qhov concentration kuj cuam tshuam rau tag nrho cov khoom tsim tawm.
Propylene glycol yog ib qho tshuaj yaj tseem ceeb hauv cov tshuaj temsirolimus uas muaj cov tshuaj ntau rau kev txhaj tshuaj, thiab nws qhov concentration cuam tshuam ncaj qha rau qhov kev yaj thiab kev ruaj khov ntawm cov tshuaj. Kev muaj propylene glycol concentration tsim nyog yuav ua kom cov tshuaj temsirolimus yaj tag nrho, tiv thaiv kev sib xyaw ua ke lossis kev nag, tswj kev ruaj khov thaum khaws cia thiab siv, thiab tiv thaiv kev txo qis ntawm kev ua haujlwm lossis kev ua tsis tiav vim kev sib xyaw tsis raug.
Kev siv tshuaj propylene glyco sib txawv nyob rau hauv cov kev siv tshwj xeeb. Hauv kev lag luam tshuaj, qhov yuav tsum tau ua kom muaj kev sib xyaw yog qhov nruj heev. Raws li Tebchaws Meskas Pharmacopeia (USP), nws qhov kev sib xyaw hauv cov tshuaj txhaj yuav tsum tsis pub tshaj 30% (v/v), thiab qhov siab tshaj plaws ib zaug noj rau kev npaj noj yuav tsum qis dua 25 mg/kg ntawm qhov hnyav ntawm lub cev.
Peb Qhov Kev Sib Tw ntawm Kev Tswj Xyuas Kev Xav Ib Txwm Muaj
Kev Ntsuas Tes Uas Siv Sijhawm Thiab Siv Zog Ntau Thiab Tsis Zoo
Kev kuaj xyuas qhov concentration ntawm propylene glycol yog siv kev kuaj tes thiab kev tshuaj ntsuam hauv chaw kuaj mob hauv kev tsim khoom ib txwm muaj. Feem ntau nws siv sijhawm ob peb teev kom tau txais cov txiaj ntsig thaum tsis muaj kev nyeem ntawv meej meej thaum tos.
Qhov kev hloov pauv ntawm qhov concentration yuav ua rau cov khoom tsis ua haujlwm ntau, kev tsim khoom nres, thiab cov khoom siv tsis ua haujlwm, ua rau lub voj voog tsim khoom ntev dua thiab ua rau lub sijhawm siv nyiaj ntau dua. Cov ntaub ntawv qhia tias tsuas yog kev ncua sijhawm hauv kev sim concentration thiaj li ua rau lub sijhawm tsim khoom poob ntau txhua xyoo.
Kev Hloov Pauv ntawm Kev Ntsuas Tsis Tswj Tau
Cov tshuaj Temsirolimus uas muaj zog rau kev txhaj tshuaj xav tau qhov concentration ntawm propylene glycol kom raug, vim tias txawm tias qhov kev hloov pauv me me xwb los kuj tuaj yeem cuam tshuam rau kev ruaj khov thiab kev nyab xeeb ntawm cov tshuaj. Qhov kev sim tes tsawg tsawg ua rau nws tsis tuaj yeem ntes tau qhov kev hloov pauv ntawm qhov concentration tiag tiag, ua rau kev hloov kho tsis raws sijhawm.
Kev hloov pauv ntawm cov kev ntsuas ib txwm muaj yuav ua rau muaj teeb meem zoo xws li qhov tsis huv lossis nag, uas ua rau muaj kev phiv tshuaj loj heev, ua rau lub koob npe nrov ntawm lub tuam txhab puas tsuaj, thiab txawm tias ua rau muaj kev pheej hmoo rov qab los yog kev tsis sib haum xeeb raws li txoj cai.
Cov Khoom Siv Uas Muab Zais Cia
Kev sim tes ntau zausrequkev chim siab ntauntawmcov neeg ua haujlwm, cov khoom siv, thiab lub sijhawm. Ntxiv mus, kev tswj hwm qhov kev sib sau ua ke tsis raug ua rau cov khoom siv raw pov tseg, kev ua haujlwm dua tshiab, thiab cov khoom siv hnav, tsim cov nqi zais loj heev. Piv txwv li, lub tuam txhab tshuaj nruab nrab yuav raugmmobions of lossvim yog kev tswj hwm qhov concentration ntawm propylene glycol tsis raug, uas yog los ntawm cov khoom siv raw pov tseg thiab kev ua haujlwm dua.
Qhov Yuav Tsum Tau Tswj Kev Xav Tau
Asib qho khoom siv tseem ceeb hauv cov tshuaj temsirolimus uas muaj zog rau kev txhaj tshuaj,lub zooty and peraukev ua siab loj of final ddaim ntaub pua plags depend on lub concenkev sib raug zoon of propylene glycol. Qhov concentration ntawm propylene glycol uas tsim nyog ua kom cov tshuaj yaj tau thiab ruaj khov thaum txo qhov khaus kom ntseeg tau tias tus neeg mob muaj kev nyab xeeb.
Kev daws teeb meem rau kev txo nqi thiab kev txhim kho kev ua haujlwm zoo
Ntsib cov teeb meem ntawm kev tswj hwm kev xav ib txwm muaj, Lonnmeter's inline concentration meter, nrog nws cov kev ua tau zoo tshaj plaws, tau dhau los ua "riam phom zais cia" rau cov tuam txhab tshuaj kom ua tiav kev tsim khoom meej, txo cov nqi, thiab txhim kho kev ua haujlwm zoo.
Kev Saib Xyuas Lub Sijhawm Tiag Tiag, Kev Tswj Xyuas Kom Tseeb
Lonnmeter lub tshuab ntsuas qhov ntsuas inline siv cov yam ntxwv ntawm kev co ntawm lub fork thiab cov algorithms ntse los saib xyuas qhov ntsuas ntawm propylene glycol hauv lub sijhawm tiag tiag thiab txuas ntxiv mus, xa cov ntaub ntawv mus rau lub kaw lus tswj kev tsim khoom hauv ob peb feeb xwb. Cov neeg ua haujlwm tuaj yeem ntes tau qhov hloov pauv ntawm qhov ntsuas tam sim ntawd thiab ua qhov kev hloov kho kom raug kom tswj tau qhov ruaj khov hauv cov qauv txheem. Nws qhov tseeb ntawm 0.003 g / ml ntau dua li cov qib nruab nrab ntawm kev lag luam.
Kev Tswj Xyuas Tsis Siv Neeg, Kev Ua Haujlwm Zoo Dua
Lub 'meter' muaj cov khoom siv sib txuas ua ke zoo, sib txuas nrog ntau yam tshuab tsim khoom. Thaum pom qhov sib txawv ntawm cov nqi teeb tsa, nws cia li ua rau muaj kev ua xws li ntxiv kua lossis do yam tsis muaj kev cuam tshuam tes, ua rau muaj kev tswj hwm cov txheej txheem tag nrho. Qhov no txo qhov yuam kev ntawm tib neeg thiab lub sijhawm thaum ua kom muaj txiaj ntsig zoo dua. Hauv kev tshawb fawb txog ib lub tuam txhab tshuaj nto moo, kev qhia txog Lonnmeter's inline concentration meter txo cov voj voog tsim khoom rau temsirolimus concentrated solution los ntawm qhov nruab nrab ntawm 30%, nrog rau kev nce ntxiv ntawm lub peev xwm.
Kev Pov Hwm Zoo, Txo Kev Pheej Hmoo
Los ntawm kev tswj qhov concentration kom raug, Lonnmeter lub ntsuas concentration inline tiv thaiv tau cov teeb meem zoo ntawm cov tshuaj uas tshwm sim los ntawm kev hloov pauv ntawm concentration, txo qis qhov kev ua tsis tiav ntawm cov tshuaj thiab kev pheej hmoo ntawm kev rov qab los. Nws lub kaw lus saib xyuas zoo ntau yam uas ua rau nws ntse thiab kwv yees qhov sib txawv ntawm kev concentration, ua ntej txo cov kev pheej hmoo uas yuav tshwm sim. Kev tswj qhov concentration ruaj khov kuj ua rau muaj kev sib xws ntawm cov tshuaj ntau ntau, ua kom cov khoom sib tw hauv kev ua lag luam muaj zog.
Cov txiaj ntsig mus sij hawm ntev, Kev txhim kho tus nqi
Txawm hais tias qhov kev nqis peev thawj zaug hauv Lonnmeter lub ntsuas inline concentration yog qhov siab heev, nws txoj kev txhim kho tus nqi mus sij hawm ntev yog qhov tseem ceeb. Los ntawm kev txo cov khoom siv pov tseg, txo cov nqi rov ua haujlwm, thiab txo cov khoom siv hnav, cov tuam txhab tuaj yeem tswj cov nqi tsim khoom tau zoo. Cov ntaub ntawv tiag tiag qhia tau tias kev siv Lonnmeter lub ntsuas tuaj yeem txuag tau ntau dua 20% txhua xyoo ntawm cov khoom siv raw thiab cov nqi rov ua haujlwm. Tsis tas li ntawd, kev txhim kho kev ua haujlwm zoo dua thiab cov khoom zoo txhais tau tias muaj kev rov qab los ntawm kev lag luam siab dua, ua tiav kev txo nqi tiag tiag thiab kev ua haujlwm zoo dua.
Hauv nthwv dej ntawm kev txhim kho zoo hauv kev lag luam biopharmaceutical, kev tswj hwm qhov tseeb tau dhau los ua qhov tseem ceeb hauv kev txhim kho kev sib tw. Lonnmeter's inline concentration meter tsis yog tsuas yog muab cov thev naus laus zis siab heev thiab kev ua tau zoo txhim khu kev qha xwb tab sis kuj muab cov kev daws teeb meem tshwj xeeb thiab kev txhawb nqa tom qab muag. Txawm hais tias hloov kho rau cov txheej txheem tsim khoom nyuaj lossis muab kev txhawb nqa 24/7, peb cog lus tias yuav tiv thaiv koj cov txheej txheem tsim khoom. Tiv tauj peb hnub no kom tau txais koj cov kev daws teeb meem saib xyuas kev tsom xam!
Lub sijhawm tshaj tawm: Lub Rau Hli-03-2025
